“The burden of Babylon, which Isaiah the son of Amoz did see.”
That is, the great calamity, which was prophesied to come on Babel, as a most grievous burden, which they were not able to bear. In these twelve chapters following, he speaketh of the plagues wherewith God would smite the strange nations (whom they knew) to declare that God chastised the Israelites as his children, and these others as his enemies: and also if that God spare not these that are ignorant, that they must not think strange, if he punish them which have knowledge of his Law, and keep it not.